PHARMExcel CRO has partnered with Barking and Havering NHS Trust to manage a UK-based, investigator-led exploratory neuroscience study using a next-generation brain–machine interface. The research programme is funded by a grant from the Advanced Research and Invention Agency (ARIA). The research platform, known as the Forest system, uses ultrasound technology to image and study brain activity in order to advance our understanding of how the brain works. The research platform has been developed by Los Angeles-based Focused Research Organisation Forest Neurotech.
Unlike existing neuroscience techniques such as deep brain stimulation, which access only a single area of the brain, this technology can image and interrogate the whole brain with high spatial precision.
As the academic sponsor and project lead, Barking and Havering NHS Trust brings scientific leadership and specialist neuroscience expertise. PHARMExcel, as CRO, ensures robust study management, governance oversight, and quality compliance to support the success of this ground-breaking research programme.
Together, the collaboration combines academic independence with commercial efficiency—accelerating the research pathway for a transformative neuroscience platform.
PHARMExcel provides a flexible, ‘pick and mix’ service offering – allowing the Sponsor to engage the specific services they need tailored to the study requirements which include:
This project demanded a UK CRO company experienced in complex research studies and academic collaboration. PHARMExcel’s expertise in research governance, particularly with novel research technologies, will ensure that the Forest programme maintains full compliance with NHS R&D and research ethics requirements.
Our agile team supports rapid ethics submissions and works closely with the Trust to align academic goals with professional research standards, ensuring the study launches on time, with participant safety and scientific rigour front and centre.
Through our proactive collaboration, the study will be able to begin generating foundational neuroscience data on this novel technology faster than traditional models.
Academic research sponsor
Principal investigator
Research technology partner
Key team members at Forest Neurotech:
Individuals with a decompressive craniectomy (e.g. from traumatic brain injury, stroke, or infection).
PHARMExcel brings a commercially efficient, academically sensitive approach to the trial. As a development partner, we deliver an ISO-accredited infrastructure, expert project coordination, and clear regulatory pathways—enabling quality outcomes from the clinical trial.
“PHARMExcel understands the needs of academic-led innovation. Our team brings structure, speed, and quality to this complex neurotechnology study—ensuring patient safety, regulatory compliance, and progress. It’s a true partnership.” Yvanne Enever, CEO & Founder of PHARMExcel
